We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 9-?-D-Ribofuranosyl-9H-purin-6-amine Order number: 211526 CAS: 5682-25-7 Purity: 95% Appearance: SOLID MF: C10H13N5O4 MW: 267.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Benzamide, N-(9-?-D-ribofuranosyl-9H-purin-6-yl)-(8CI) Order number: 211528 CAS: 4546-55-8 Purity: 97% Appearance: SOLID MF: C17H17N5O5 MW: 371.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-Azacytidine Order number: 211529 CAS: 320-67-2 Purity: 98% Appearance: SOLID MF: C8H12N4O5 MW: 244.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: D-Ribonic acid, 2,3-O-(1-methylethylidene)-, ?-lactone Order number: 211530 CAS: 30725-00-9 Purity: 99% Appearance: WHITE POWDER MF: C8H12O5 MW: 188.2 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 1-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione Order number: 211531 CAS: 2140-76-3 Purity: 98% Appearance: OFF-WHITE POWDER MF: C10H14N2O6 MW: 258.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 9-?-D-Arabinofuranosylguanine Order number: 211532 CAS: 38819-10-2 Purity: 98% Appearance: SOLID MF: C10H13N5O5 MW: 283.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |