We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 5'-Deoxy-5-fluoro-N-[(pentyloxy)carbonyl]cytidine Order number: 211536 CAS: 154361-50-9 Purity: 98% Appearance: SOLID MF: C15H22FN3O6 MW: 359.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: L-()-Ribos Order number: 211538 CAS: 24259-59-4 Purity: 97% Appearance: SOLID MF: C5H10O5 MW: 150.1 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 2'-Deoxy-2',2'-difluorocytidine Order number: 211539 CAS: 95058-81-4 Purity: 98% Appearance: SOLID MF: C9H11F2N3O4 MW: 263.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: N-Acetylcytidine Order number: 211540 CAS: 3768-18-1 Purity: 97% Appearance: SOLID MF: C11H15N3O6 MW: 285.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: (3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one Order number: 211542 CAS: 55094-52-5 Purity: 98% Appearance: WHITE POWDER MF: C26H26O5 MW: 418.5 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 2'-C-Methyluridine Order number: 211543 CAS: 31448-54-1 Purity: 97% Appearance: SOLID MF: C10H14N2O6 MW: 258.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |