We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 5-Iodo-2'-deoxycytidine Order number: 211544 CAS: 611-53-0 Purity: 98% Appearance: SOLID MF: C9H12IN3O4 MW: 353.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Tetrahydrouridine Order number: 211545 CAS: 18771-50-1 Purity: 80% Appearance: SOLID MF: C9H16N2O6 MW: 248.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: (2R,3R,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-((((lr,3S)-3-(2-(5-(tert-butyl)-lH-benzo[d]imidazol2yl)ethyl)cyclobutyl)(isopropyl)amino)methyl)tetrahydrofuran-3,4-diol Order number: 211547 CAS: 1380288-87-8 Purity: ?98% Appearance: SOLID MF: C30H42N8O3 MW: 562.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 1-?-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide Order number: 211548 CAS: 36791-04-5 Purity: 98% Appearance: SOLID MF: C8H12N4O5 MW: 244.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2'-Deoxyguanosine Order number: 211549 CAS: 961-07-9 Purity: 95% Appearance: SOLID MF: C10H13N5O4 MW: 267.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2,2'-Anhydro(1-?-D-arabinofuranosyl)uracil Order number: 211550 CAS: 3736-77-4 Purity: 98% Appearance: SOLID MF: C9H10N2O5 MW: 226.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |