We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: (2R,3S)-5-Chloro-2-(((4-chlorobenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-chlorobenzoate Order number: 211566 CAS: 3601-90-9 Purity: 90% Appearance: SOLID MF: C19H15Cl3O5 MW: 429.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2?,3?-Dideoxy-5-iodouridine Order number: 211567 CAS: 105784-83-6 Purity: 97% Appearance: SOLID MF: C9H11IN2O4 MW: 338.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(6-amino-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate Order number: 211568 CAS: 7387-57-7 Purity: 98% Appearance: SOLID MF: C16H19N5O7 MW: 393.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2',3',5'-Tri-O-acetylguanosine Order number: 211569 CAS: 6979-94-8 Purity: 95% Appearance: WHITE POWDER MF: C16H19N5O8 MW: 409.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2',3',5'-Tri-O-acetyluridine Order number: 211570 CAS: 4105-38-8 Purity: 97% Appearance: SOLID MF: C15H18N2O9 MW: 370.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2,3,5-Tri-O-benzyl-D-ribofuranose Order number: 211571 CAS: 89615-45-2 Purity: 97% Appearance: SOLID MF: C26H28O5 MW: 420.5 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |