We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: (3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyldihydrofuran-2(3H)-one Order number: 211578 CAS: 492-30-8 Purity: 99% Appearance: SOLID MF: C6H10O5 MW: 162.1 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 3'-Deoxycytidine Order number: 211580 CAS: 7057-33-2 Purity: 98% Appearance: SOLID MF: C9H13N3O4 MW: 227.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 3-O-BENZYL-4-(HYDROXYMETHYL-1,2-O-ISOPROPYLIDENE)-ALPHA-D-ERYTHROPENTOFURANOSE Order number: 211581 CAS: 63593-03-3 Purity: 95% Appearance: OFF-WHITE POWDER? MF: C16H22O6 MW: 310.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5,6-Diamino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione Order number: 211582 CAS: 5440-00-6 Purity: 98% Appearance: SOLID MF: C6H10N4O2 MW: 170.2 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 5-Bromo-4-chloro-3-(beta-D-galactopyranosyloxy)indole Order number: 211583 CAS: 7240-90-6 Purity: 98% Appearance: SOLID MF: C14H15BrClNO6 MW: 408.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-Bromo-6-chloro-3-indolyl-beta-D-galactoside Order number: 211584 CAS: 93863-88-8 Purity: 98.0(HPLC)% Appearance: SOLID MF: C14H15BrClNO6 MW: 408.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |