We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione Order number: 211585 CAS: 316-46-1 Purity: 98% Appearance: SOLID MF: C9H11FN2O6 MW: 262.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-IODOCYTOSINE Order number: 211587 CAS: 1122-44-7 Purity: 98% Appearance: SOLID MF: C4H4IN3O MW: 237 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 6-Azuridine Order number: 211588 CAS: 54-25-1 Purity: 98% Appearance: SOLID MF: C8H11N3O6 MW: 245.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-O-tert-Butyldimethylsilyl-2,3-O-isopropylidene-alpha,beta-D-ribofuranose Order number: 211589 CAS: 68703-51-5 Purity: n.a.% Appearance: SOLID MF: C14H28O5Si MW: 304.5 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 5-O-tert-Butyldiphenylsilyl-2,3-O-isopropylidene-D-ribofuranose Order number: 211590 CAS: 141607-35-4 Purity: n.a.% Appearance: n.a. MF: C24H32O5Si MW: 428.6 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 7H-Pyrrolo[2,3-d]pyrimidin-4-amine,7-(2-deoxy-b-D-erythro-pentofuranosyl)- Order number: 211592 CAS: 60129-59-1 Purity: ?97% Appearance: SOLID MF: C11H14N4O3 MW: 250.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |