Amino Acids, Nucleosides and Nucleotides

Amino Acids

We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.

Nucleosides and Nucleoside Phosphoramidites

We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.

Nucleotides

dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.

Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.

  • Amino Acids for Stapled Peptides
  • 2-Methylated Amino Acids
  • Peptide Labeling
  • Other Unnatural Amino Acids
  • Nucleosides
  • HNA Precursors
  • Morpholino Nucleosides
  • Nucleoside Phosphoramidites and Nucleotides
  • Other Unnatural Amino Acids

    Structure Details
    Product Name: Fmoc-Lys(FOR)-OH
    Order number: 204524
    CAS: 201004-23-1
    Purity: >=95%
    Appearance: solid
    MF: C22H24N2O5
    MW: 396.443
    MP: n.a. oC

    Description:
    This is a derivative of the lysine derived amino acid.
    Product Name: Fmoc-lys(palmitoyl)-OH
    Order number: 204526
    CAS: 201004-46-8
    Purity: >=95%
    Appearance: solid
    MF: C37H54N2O5
    MW: 606.848
    MP: n.a. oC

    Description:
    This is a lysine derived amino acid with a lipid chain.
    Product Name: Fmoc-Lys(ipr,Boc)-OH
    Order number: 204528
    CAS: 201003-48-7
    Purity: >=95%
    Appearance: solid
    MF: C29H38N2O6
    MW: 510.631
    MP: n.a. oC

    Description:
    This is a derivative of the lysine derived amino acid.
    Product Name: Lysine(butyryl)-OH
    Order number: 204530
    CAS: 75396-30-4
    Purity: >=95%
    Appearance: solid
    MF: C11H22N2O3
    MW: 230.308
    MP: n.a. oC

    Description:
    This is a derivative of the lysine derived amino acid.
    Product Name: Lysine(crotonyl)-OH
    Order number: 204531
    CAS: 1338823-35-0
    Purity: >=95%
    Appearance: solid
    MF: C10H18N2O3
    MW: 214.265
    MP: n.a. oC

    Description:
    This is a derivative of the lysine derived amino acid.
    Product Name: Lysine(succinyl)-OH
    Order number: 204532
    CAS: 52685-16-2
    Purity: >=95%
    Appearance: solid
    MF: C10H18N2O5
    MW: 246.263
    MP: n.a. oC

    Description:
    This is a derivative of the lysine derived amino acid.