We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Tubercidin Order number: 204541 CAS: 69-33-0 Purity: >=95% Appearance: solid MF: C11H14N4O4 MW: 266.257 MP: n.a. oC Description: Tubercidin and deazapurine nucleosides have been studied for activities against Covid (SARS-CoV-2) virus. |
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Product Name: 8-Iodoadenosine Order number: 204550 CAS: 31281-88-6 Purity: >=95% Appearance: solid MF: C10H12IN5O4 MW: 393.141 MP: n.a. oC Description: This is a useful compound for nucleic acid study and drug discovery use. 8-substitured purine nucleosides have been studied for antagonism on A2A receptor. |
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Product Name: 4-Chloro-7H-pyrrolo[2,3-d]pyrimidine Order number: 204554 CAS: 3680-69-1 Purity: >=95% Appearance: solid MF: C6H4ClN3 MW: 153.569 MP: n.a. oC Description: Heterocycle and nucleoside building block. |
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Product Name: 7H-Pyrrolo[2,3-d]pyrimidin-4-amine Order number: 204555 CAS: 1500-85-2 Purity: >=95% Appearance: solid MF: C6H6N4 MW: 134.142 MP: n.a. oC Description: Heterocycle and nucleoside building block. |
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Product Name: 7H-Pyrrolo[2,3-d]pyrimidine-2,4-diamine Order number: 204556 CAS: 18620-92-3 Purity: >=95% Appearance: solid MF: C6H7N5 MW: 149.157 MP: n.a. oC Description: Heterocycle and nucleoside building block. |
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Product Name: 1H-Pyrrolo[2,3-d]pyrimidine-2,4-(3H,7H)-dione Order number: 204558 CAS: 39929-79-8 Purity: >=95% Appearance: solid MF: C6H5N3O2 MW: 151.125 MP: n.a. oC Description: Heterocycle and nucleoside building block. |