We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 8-BROMOGUANOSINE DIHYDRATE Order number: 211593 CAS: 332359-99-6 Purity: 98% Appearance: SOLID MF: C10H14BrN5O6 MW: 380.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: ACETIC ACID (2R,3R,4R,5R)-3,4-DIACETOXY-5-(6-CHLORO-2-IODO-PURIN-9-YL)-TETRAHYDRO-FURAN-2-YLMETHYL ESTER Order number: 211594 CAS: 5987-76-8 Purity: 97% Appearance: SOLID MF: C16H16ClIN4O7 MW: 538.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Beta-D-Ribofuranose 1,2,3,5-tetraacetate Order number: 211596 CAS: 13035-61-5 Purity: 97% Appearance: SOLID MF: C13H18O9 MW: 318.3 MP: n.a. oC Description: Useful building block for nucleoside and nucleotide chemistry |
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Product Name: Cladribine Order number: 211597 CAS: 4291-63-8 Purity: ?98% Appearance: SOLID MF: C10H12ClN5O3 MW: 285.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Cytidine 2:3-Cyclic Monophosphate Sodium Salt Order number: 211598 CAS: 15718-51-1 Purity: 95% Appearance: SOLID MF: C9H12N3NaO7P MW: 328.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Cytidine sulfate Order number: 211600 CAS: 32747-18-5 Purity: 98% Appearance: WHITE POWDER MF: C9H15N3O9S MW: 341.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |