We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: D-Ribono-1,4-lactone Order number: 211601 CAS: 5336-08-3 Purity: 97% Appearance: SOLID MF: C5H8O5 MW: 148.1 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: Sodium ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate Order number: 211603 CAS: 3387-36-8 Purity: 98% Appearance: SOLID MF: C9H11N2Na2O9P MW: 368.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Gemcitabine hydrochloride Order number: 211604 CAS: 122111-03-9 Purity: 98% Appearance: WHITE POWDER MF: C9H12ClF2N3O4 MW: 299.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Methyl 2,3:4,6-Di-O-benzylidene-?-D-mannopryanoside Order number: 211606 CAS: 4148-71-4 Purity: ?98.0(HPLC)% Appearance: SOLID MF: C21H22O6 MW: 370.4 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: Methyl b-D-ribofuranoside Order number: 211607 CAS: 7473-45-2 Purity: 97% Appearance: WHITE SOLID MF: C6H12O5 MW: 164.2 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: N-Isobutyrylguanosine Order number: 211608 CAS: 64350-24-9 Purity: 98% Appearance: WHITE POWDER MF: C14H19N5O6 MW: 353.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |