We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: VIDARABINE G-2939UG/ mg(AI) Order number: 211619 CAS: 24356-66-9 Purity: 98% Appearance: SOLID MF: C10H15N5O5 MW: 285.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: (3S,4R)-Methyl 3-(4-chlorobenzoyl)-6-(4-chlorophenyl)-3,4,5-trihydroxy-6-oxohexanoate Order number: 211620 CAS: 99886-53-0 Purity: ? 95 (HPLC)% Appearance: n.a. MF: C20H18Cl2O7 MW: 441.3 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 5'-Chloro-5'-deoxyadenosine Order number: 211621 CAS: 892-48-8 Purity: 97% Appearance: SOLID MF: C10H12ClN5O3 MW: 285.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2,3,5-Tri-O-benzyl-b-D-ribofuranose Order number: 211622 CAS: 89361-52-4 Purity: n.a.% Appearance: SOLID MF: C26H28O5 MW: 420.5 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 2-Amino-9-((2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one Order number: 211623 CAS: 85326-06-3 Purity: 95% Appearance: POWDER MF: C10H13N5O3 MW: 251.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-Methyl-2'-deoxycytidine Order number: 211625 CAS: 838-07-3 Purity: 98% Appearance: SOLID MF: C10H15N3O4 MW: 241.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |