We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-adenosine Order number: 211628 CAS: 81352-25-2 Purity: 95% Appearance: SOLID MF: C31H31N5O6 MW: 569.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5'-O-DMT-2'-O-TBDMS-N-Bz-Adenosine Order number: 211629 CAS: 81265-93-2 Purity: 95% Appearance: SOLID MF: C44H49N5O7Si MW: 788 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 4-Methylumbelliferyl ?-L-arabinofuranoside Order number: 211631 CAS: 77471-44-4 Purity: ?96% Appearance: n.a. MF: C15H16O7 MW: 308.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine Order number: 211632 CAS: 76512-82-8 Purity: ? 99.5 (HPLC)% Appearance: WHITE POWDER MF: C30H31N3O6 MW: 529.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2'-Fluoro -2'-deoxyguanosine Order number: 211633 CAS: 78842-13-4 Purity: 97% Appearance: WHITE POWDER MF: C10H12FN5O4 MW: 285.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: (2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-3-ol Order number: 211634 CAS: 75059-22-2 Purity: 98% Appearance: SOLID MF: C10H12FN5O3 MW: 269.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |