We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 6-O-Methyl Guanosine Order number: 211635 CAS: 7803-88-5 Purity: 98% Appearance: LIQUID MF: C11H15N5O5 MW: 297.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: (e)-5-(2-carboxyvinyl)-2-deoxyuridine Order number: 211636 CAS: 74131-06-9 Purity: n.a.% Appearance: SOLID MF: C12H14N2O7 MW: 298.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2-Amino-2'-O-methyl-adenosine Order number: 211637 CAS: 80791-87-3 Purity: 98% Appearance: SOLID MF: C11H16N6O4 MW: 296.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5'-O-DMT-2'-O-iBu-N-Bz-Guanosine Order number: 211640 CAS: 81279-39-2 Purity: 95% Appearance: SOLID MF: C41H51N5O8Si MW: 770 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: N4-Benzoyl-5'-O-(4,4'-diMethoxytrityl)-2'-deoxycytidine Order number: 211642 CAS: 67219-55-0 Purity: 98% Appearance: WHITE POWDER MF: C37H35N3O7 MW: 633.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5'-O-Tritylthymidine Order number: 211644 CAS: 7791-71-1 Purity: 98 (contains <10DCM)% Appearance: SOLID MF: C29H28N2O5 MW: 484.5 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |