We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione Order number: 211645 CAS: 951-78-0 Purity: ?99% Appearance: SOLID MF: C9H12N2O5 MW: 228.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Thymidine, 4-thio- Order number: 211646 CAS: 7236-57-9 Purity: n.a.% Appearance: SOLID MF: C10H14N2O4S MW: 258.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)uracil Order number: 211650 CAS: 69123-94-0 Purity: 95% Appearance: WHITE POWDER MF: C9H11FN2O5 MW: 246.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 3-DEAZAADENOSINE Order number: 211653 CAS: 6736-58-9 Purity: 99% Appearance: SOLID MF: C11H14N4O4 MW: 266.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 3'-DEOXYURIDINE Order number: 211655 CAS: 7057-27-4 Purity: 98% Appearance: WHITE POWDER MF: C9H12N2O5 MW: 228.2 MP: n.a. oC Description: Useful building block for nucleoside and nucleotide chemistry |
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Product Name: 1-O-Acetyl-2,3,5-Tri-O-benzoyl-beta-D-Ribofuranose Order number: 211656 CAS: 6974-32-9 Purity: 98% Appearance: SOLID MF: C28H24O9 MW: 504.5 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |