We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: PD 117519 Order number: 211657 CAS: 96392-15-3 Purity: 95% Appearance: WHITE POWDER MF: C19H21N5O4 MW: 383.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 1,2-DIDEOXY-D-RIBOFURANOSE Order number: 211658 CAS: 91547-59-0 Purity: 98% Appearance: LIQUID MF: C5H10O3 MW: 118.1 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: S-(5'-deoxyadenosin-5'-yl)-L-Homocysteine Order number: 211659 CAS: 979-92-0 Purity: ?98% Appearance: SOLID MF: C14H20N6O5S MW: 384.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-HYDROXYURIDINE Order number: 211660 CAS: 957-77-7 Purity: 96% Appearance: SOLID MF: C9H12N2O7 MW: 260.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-Bromo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione Order number: 211661 CAS: 957-75-5 Purity: 98% Appearance: SOLID MF: C9H11BrN2O6 MW: 323.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Cytidine, 2'-deoxy-5-ethynyl- Order number: 211662 CAS: 69075-47-4 Purity: 98% Appearance: SOLID MF: C11H13N3O4 MW: 251.2 MP: n.a. oC Description: Useful building block for nucleoside and nucleotide chemistry |