We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 2-Amino-9-((2R,4S,5S)-4-amino-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one Order number: 211666 CAS: 66323-49-7 Purity: n.a.% Appearance: SOLID MF: C10H14N6O3 MW: 266.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5'-Amino-5'-deoxyadenosine Order number: 211667 CAS: 14365-44-7 Purity: 98% Appearance: n.a. MF: C10H14N6O3 MW: 266.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: N4-Benzoyl-2'-deoxycytidine Order number: 211669 CAS: 4836-13-9 Purity: 97% Appearance: SOLID MF: C16H17N3O5 MW: 331.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: (2S,3R,5R)-5-Chloro-2-(((4-methylbenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-methylbenzoate Order number: 211670 CAS: 141846-57-3 Purity: 90% Appearance: SOLID MF: C21H21ClO5 MW: 388.8 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5'-Tosyladenosine Order number: 211671 CAS: 5135-30-8 Purity: 95% Appearance: SOLID MF: C17H19N5O6S MW: 421.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2'-O-(2-Methoxyethyl)-cytidine Order number: 211672 CAS: 223777-16-0 Purity: 95% Appearance: SOLID MF: C12H19N3O6 MW: 301.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |