We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Fmoc-N-omega-Me- Lys(Boc)-OH Order number: 204533 CAS: 197632-76-1 Purity: >=95% Appearance: solid MF: C27H34N2O6 MW: 482.577 MP: n.a. oC Description: This is a orthogonally protected lysine. |
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Product Name: Fmoc-Lys(DDE)-OH Order number: 204537 CAS: 150629-67-7 Purity: >=95% Appearance: solid MF: C31H36N2O6 MW: 532.637 MP: n.a. oC Description: This is a product of the lysine derived amino acids. |
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Product Name: D-Arg(Me, Me)-OH (asymmetrical) Order number: 204627 CAS: 783265-75-8 Purity: >=95% Appearance: solid MF: C8H18N4O2 MW: 202.258 MP: n.a. oC Description: N-Methylated Arg is believed a derivative of Arg in the NO pathway. As a building block, it has found applications for making peptides with nervous system activities. |
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Product Name: Fmoc-D-Arg(Me, Me)-OH (symmetrical) Order number: 204628 CAS: n/a Purity: >=95% Appearance: solid MF: C23H28N4O4 MW: 424.501 MP: n.a. oC Description: N-Methylated Arg is believed a derivative of Arg in the NO pathway. As a building block, it has found applications for making peptides with nervous system activities. |
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Product Name: Fmoc-L-HomoArg(Pbf)-OH Order number: 204630 CAS: 401915-53-5 Purity: >=95% Appearance: solid MF: C35H42N4O7S MW: 662.802 MP: n.a. oC Description: HomoArgine is derived from Arg in NO pathway. |
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Product Name: Fmoc-L-HomoArg(Pmc)-OH Order number: 204631 CAS: 214852-52-5 Purity: >=95% Appearance: solid MF: C36H44N4O7S MW: 676.829 MP: n.a. oC Description: L-Homoarginine is the naturally-occurring enantiomer. Physiologically, homoarginine serves a substrate of NOS. It may participate in pathways that Arg does. |