We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: N6-Ethenoadenosine Order number: 211682 CAS: 39007-51-7 Purity: n.a.% Appearance: SOLID MF: C12H13N5O4 MW: 291.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2-Amino-9-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-1H-purin-6(9H)-one Order number: 211684 CAS: 362-76-5 Purity: 95% Appearance: WHITE POWDER MF: C13H17N5O5 MW: 323.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: (2S,3S,4R)-5-(Allyloxy)-2,3,4-tris(benzyloxy)pentan-1-ol Order number: 211685 CAS: 111549-97-4 Purity: 90% Appearance: n.a. MF: C29H34O5 MW: 462.6 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: Isoguanosine Hydrate Order number: 211686 CAS: 359436-55-8 Purity: n.a.% Appearance: SOLID MF: C10H15N5O6 MW: 301.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Uridine, 5-bromo-,2',3',5'-triacetate (9CI) Order number: 211688 CAS: 105659-32-3 Purity: 95% Appearance: SOLID MF: C15H17BrN2O9 MW: 449.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: N-(1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-3-fluoro-4-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)acetamide Order number: 211689 CAS: 159414-98-9 Purity: 98% Appearance: n.a. MF: C32H32FN3O7 MW: 589.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |