We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
| Structure | Details |
|---|---|
|
|
Product Name: Adenosine,7,8-dihydro-8-thioxo- Order number: 211696 CAS: 3001-45-4 Purity: 97% Appearance: SOLID MF: C10H13N5O4S MW: 299.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: 1,2,4-Triazin-5(2H)-one,3,4-dihydro-2-b-D-ribofuranosyl-3-thioxo- Order number: 211697 CAS: 27089-56-1 Purity: 97% Appearance: SOLID MF: C8H11N3O5S MW: 261.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: Ac-rC Phosphoramidite Order number: 211698 CAS: 121058-88-6 Purity: 95% Appearance: WHITE POWDER MF: C47H64N5O9PSi MW: 902.1 MP: n.a. oC Description: This is a useful building block for nucleotide synthesis on solid support. |
|
|
Product Name: Adenosine,2'-deoxy-2-fluoro- Order number: 211699 CAS: 21679-12-9 Purity: n.a.% Appearance: SOLID MF: C10H12FN5O3 MW: 269.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: 4-Methylumbelliferyl beta-D-ribofuranoside Order number: 211701 CAS: 195385-93-4 Purity: ?98% Appearance: SOLID MF: C15H16O7 MW: 308.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: N6-Methyladenosine Order number: 211703 CAS: 1867-73-8 Purity: 97% Appearance: SOLID MF: C11H15N5O4 MW: 281.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |