We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
| Structure | Details |
|---|---|
|
|
Product Name: N-(1-((2R,3R,4R,5R)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-5-methyl-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide Order number: 211704 CAS: 182496-01-1 Purity: 96% Appearance: SOLID MF: C41H43N3O9 MW: 721.8 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: 2'-Amino-2'-deoxyadenosine Order number: 211705 CAS: 10414-81-0 Purity: 98% Appearance: SOLID MF: C10H14N6O3 MW: 266.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: Adenosine, N-[(3-hydroxyphenyl)methyl]- Order number: 211706 CAS: 110505-76-5 Purity: 97% Appearance: SOLID MF: C17H19N5O5 MW: 373.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: Inosine,2-chloro-6-O-methyl- (9CI) Order number: 211707 CAS: 15465-92-6 Purity: 96% Appearance: SOLID MF: C11H13ClN4O5 MW: 316.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: ((2R?3R?5R)-3-(Benzoyloxy)-4?4-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate Order number: 211708 CAS: 134877-42-2 Purity: 97% Appearance: SOLID MF: C20H18F2O8S MW: 456.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: 5'-O-(TERT-BUTYLDIMETHYLSILYL)-5-IODO-2'-DEOXYURIDINE Order number: 211709 CAS: 134218-81-8 Purity: 97% Appearance: SOLID MF: C15H25IN2O5Si MW: 468.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |