We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-7-(2,3,5-tri-O-acetyl-?-D-ribofuranosyl)- Order number: 211426 CAS: 16754-79-3 Purity: 97% Appearance: LIQUID MF: C17H18ClN3O7 MW: 411.8 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy- Order number: 211427 CAS: 17331-22-5 Purity: ? 99 (HPLC)% Appearance: SOLID MF: C31H31N5O5 MW: 553.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Guanosine, 2'-deoxy-N-[(dimethylamino)methylene]- Order number: 211428 CAS: 17331-13-4 Purity: 98% Appearance: SOLID MF: C13H18N6O4 MW: 322.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: D-Mannopyranosyl fluoride, 2,3,4,6-tetraacetate Order number: 211429 CAS: 174511-17-2 Purity: 95.0(GC)% Appearance: SOLID MF: C14H19FO9 MW: 350.3 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 2'-Deoxy-2'-fluorocytidine hydrate Order number: 211430 CAS: 1820580-34-4 Purity: 95% Appearance: SOLID MF: C9H14FN3O5 MW: 263.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: D-Ribose, 5-(dihydrogen phosphate), sodium salt (1:2) Order number: 211431 CAS: 18265-46-8 Purity: 85% Appearance: SOLID MF: C5H9Na2O8P MW: 274.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |