We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxyMethyl)-3-Methyltetrahydrofuran-2-yl)pyriMidine-2,4(1H,3H)-dione Order number: 211729 CAS: 114262-49-6 Purity: 98% Appearance: SOLID MF: C10H14N2O6 MW: 258.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5'-(4-Fluorosulfonylbenzoyl)adenosine hydrochloride Order number: 211730 CAS: 78859-42-4 Purity: n.a.% Appearance: n.a. MF: C17H17ClFN5O7S MW: 489.9 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Inosine,2'-deoxy-2'-fluoro- Order number: 211731 CAS: 80049-87-2 Purity: 98% Appearance: SOLID MF: C10H11FN4O4 MW: 270.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 3'-Amino-2',3'-dideoxyadenosine Order number: 211732 CAS: 7403-25-0 Purity: 99% Appearance: SOLID MF: C10H14N6O2 MW: 250.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2,3,5-Tri-O-benzoyl-2-C-methyl-D-ribonic-1,4-lactone Order number: 211733 CAS: 7392-74-7 Purity: 97% Appearance: WHITE SOLID MF: C27H22O8 MW: 474.5 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 8-HYDROXYQUINOLINE-BETA-D-GALACTOPYRANOSIDE Order number: 211736 CAS: 113079-84-8 Purity: n.a.% Appearance: n.a. MF: C15H17NO6 MW: 307.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |