We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 5'-deoxy-5'-iodouridine Order number: 211758 CAS: 14259-58-6 Purity: 97% Appearance: SOLID MF: C9H11IN2O5 MW: 354.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 1-O-ACETYL-2,3,5-TRI-O-BENZOYL-D-RIBOFURANOSE Order number: 211760 CAS: 14215-97-5 Purity: 98% Appearance: SOLID MF: C28H24O9 MW: 504.5 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 7-ALLYL-7 8-DIHYDRO-8-OXOGUANOSINE 95 Order number: 211761 CAS: 121288-39-9 Purity: 98% Appearance: WHITE POWDER MF: C13H17N5O6 MW: 339.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: L-Alanine, N-[[P(S),2'R]-2'-deoxy-2'-fluoro-2'-Methyl-P-phenyl-5'-cytidylyl]-, 1-Methylethyl ester Order number: 211763 CAS: 1334513-10-8 Purity: n.a.% Appearance: n.a. MF: C22H30FN4O8P MW: 528.5 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 6-Chloropurine -9-beta-D-(3',5'-di-O-benzoyl-2'-deoxy-2'-fluoro)arabinoriboside Order number: 211766 CAS: 135473-15-3 Purity: 97% Appearance: SOLID MF: C24H18ClFN4O5 MW: 496.9 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: (2R,3R,4R,5R)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-chloro-4-Methyltetrahydrofuran-3-yl benzoate Order number: 211769 CAS: 1496551-70-2 Purity: 95% Appearance: n.a. MF: C31H25ClN3O7- MW: 587 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |