We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: N-Fmoc-3-(2-naphthyl)-L-alanine Order number: 204636 CAS: 112883-43-9 Purity: >=95% Appearance: solid MF: C28H23NO4 MW: 437.495 MP: n.a. oC Description: This amino acid was able to be added to the genetic Code of E. coli, offering the opportunity for the expansion of the genetic code to include amino acids beyond the common 20. |
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Product Name: N-Fmoc-3-(2-naphthyl)-D-alanine Order number: 204637 CAS: 138774-94-4 Purity: >=95% Appearance: solid MF: C28H23NO4 MW: 437.495 MP: n.a. oC Description: This D-amino acid is the enantiomer of the S and its properties are yet to be explored. |
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Product Name: N-Fmoc-3-(4-pyridyl)-L-alanine Order number: 204638 CAS: 169555-95-7 Purity: >=95% Appearance: solid MF: C23H20N2O4 MW: 388.423 MP: n.a. oC Description: This is pyridine version of phenylalanine. |
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Product Name: N-Fmoc-3-(4-pyridyl)-D-alanine Order number: 204639 CAS: 205528-30-9 Purity: >=95% Appearance: solid MF: C23H20N2O4 MW: 388.423 MP: n.a. oC Description: With a phenylalanine-tRNA synthetase mutant, the synthesis of target proteins bearing iodophenyl, cyanophenyl, ethynylphenyl, azidophenyl, and pyridyl groups has been realized. |
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Product Name: N-Fmoc-3-(4-thienyl)-L-alanine Order number: 204640 CAS: 186320-06-9 Purity: >=95% Appearance: solid MF: C22H19NO4S MW: 393.457 MP: n.a. oC Description: Thienylalanine as an antiphenylalanine was studied in the Protein-depleted Rat. |
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Product Name: (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(thiazol-4-yl)propanoic acid Order number: 204641 CAS: 205528-32-1 Purity: >=95% Appearance: solid MF: C21H18N2O4S MW: 394.445 MP: n.a. oC Description: This amino acid has been reported for cosmetics use that it strengths the ability of LOXL-1 and adjusts skin aging. |