We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Nonapyrimin Order number: 204565 CAS: 5626-36-8 Purity: >=95% Appearance: solid MF: C15H24N4 MW: 260.385 MP: n.a. oC Description: Heterocycle and nucleoside building block. |
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Product Name: 3-Methyl-3H-purin-6(9H)-one Order number: 204566 CAS: 1006-11-7 Purity: >=95% Appearance: solid MF: C6H6N4O MW: 150.141 MP: n.a. oC Description: Heterocycle and nucleoside building block. |
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Product Name: 3-Methyl-3H-purine-6(9H)-thione Order number: 204567 CAS: 1006-12-9 Purity: >=95% Appearance: solid MF: C6H6N4S MW: 166.202 MP: n.a. oC Description: Heterocycle and nucleoside building block. |
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Product Name: 1,5:2,3-Dianhydro-4,6-O-[(R)-phenylmethylene]-D-allitol Order number: 204568 CAS: 92283-88-0 Purity: >=95% Appearance: solid MF: C13H14O4 MW: 234.251 MP: n.a. oC Description: This is use for intermediate for synthesis. |
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Product Name: 1,5-Anhydro-D-glucitol Order number: 204571 CAS: 154-58-4 Purity: >=95% Appearance: solid MF: C6H12O5 MW: 164.157 MP: n.a. oC Description: Sugar building block. |
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Product Name: 5-Fluorouracil Order number: RT-H96-010 CAS: 51-21-8 Purity: >=95% Appearance: solid MF: C4H3FN2O2 MW: 130.078 MP: 278 oC Description: This is a useful fluorinated nucleoside base. |