We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: METHYLMERCAPTO-D-GALACTOPYRANOSIDE Order number: 211791 CAS: 155-30-6 Purity: 98% Appearance: SOLID MF: C7H14O5S MW: 210.2 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 1-Chloro-3,5-di-(4-chlorobenzoyl)-2-deoxy-D-ribose Order number: 211793 CAS: 21740-23-8 Purity: 98% Appearance: WHITE SOLID POWDER MF: C19H15Cl3O5 MW: 429.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2,3-O-ISOPROPYLIDENE-BETA-D-RIBOFURANOSYLAMINE P-TOLUENESULFONATE SALT Order number: 211794 CAS: 29836-10-0 Purity: n.a.% Appearance: SOLID MF: C15H23NO7S MW: 361.4 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 2'-Deoxyguanosine monohydrate Order number: 211795 CAS: 312693-72-4 Purity: 97% Appearance: SOLID MF: C10H15N5O5 MW: 285.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: N6,N6-DIMETHYLADENOSINE Order number: 211797 CAS: 2620-62-4 Purity: 97% Appearance: SOLID MF: C12H17N5O4 MW: 295.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: N2-METHYLGUANOSINE Order number: 211798 CAS: 2140-77-4 Purity: 95% Appearance: SOLID MF: C11H15N5O5 MW: 297.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |