We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
| Structure | Details |
|---|---|
|
|
Product Name: Adenosine, 5'-aMino-5'-deoxy-2',3'-O-(1-Methylethylidene)- Order number: 211802 CAS: 21950-36-7 Purity: 98% Appearance: SOLID MF: C13H18N6O3 MW: 306.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: 8-oxoadenosine Order number: 211803 CAS: 29851-57-8 Purity: 98% Appearance: SOLID MF: C10H13N5O5 MW: 283.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: 2'-AMINO-D-CYTIDINE Order number: 211804 CAS: 26889-42-9 Purity: n.a.% Appearance: n.a. MF: C9H14N4O4 MW: 242.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: 2'-O-Methylguanosine Order number: 211805 CAS: 2140-71-8 Purity: 98% Appearance: OFF-WHITE POWDER MF: C11H15N5O5 MW: 297.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: 3-methylcytidine Order number: 211806 CAS: 2140-64-9 Purity: 98% Appearance: SOLID MF: C10H15N3O5 MW: 257.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
|
|
Product Name: DMT-2?-O-Me-rG(ib) amidite Order number: 211807 CAS: 251647-55-9 Purity: 95% Appearance: YELLOW POWDER MF: C47H60N7O10P MW: 914 MP: n.a. oC Description: This is a useful building block for nucleotide synthesis on solid support. |