We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 2'-DEOXY-L-URIDINE Order number: 211820 CAS: 31501-19-6 Purity: n.a.% Appearance: n.a. MF: C9H12N2O5 MW: 228.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: S-ADENOSYL-L-METHIONINE IODIDE SALT Order number: 211822 CAS: 3493-13-8 Purity: 80 (HPLC)% Appearance: n.a. MF: C15H23IN6O5S MW: 526.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: N6-CYCLOPENTYLADENOSINE Order number: 211824 CAS: 41552-82-3 Purity: 98% Appearance: SOLID MF: C15H21N5O4 MW: 335.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-METHOXYURIDINE Order number: 211825 CAS: 35542-01-9 Purity: 95% Appearance: SOLID MF: C10H14N2O7 MW: 274.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-METHYL-2-THIOURIDINE Order number: 211826 CAS: 32738-09-3 Purity: 95% Appearance: n.a. MF: C10H14N2O5S MW: 274.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2-Deoxy-D-ribonic-1,4-lactone Order number: 211827 CAS: 34371-14-7 Purity: 97% Appearance: LITTLE YELLOWLIQUID MF: C5H8O4 MW: 132.1 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |