We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 5'-IODO-5'-DEOXYADENOSINE Order number: 211828 CAS: 4099-81-4 Purity: 95% Appearance: SOLID MF: C10H12IN5O3 MW: 377.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2',3'-O-isopropylidene cytidine Order number: 211829 CAS: 362-42-5 Purity: 98% Appearance: SOLID MF: C12H17N3O5 MW: 283.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 6-METHYLMERCAPTOPURINE RIBOSIDE Order number: 211830 CAS: 342-69-8 Purity: n.a.% Appearance: SOLID MF: C11H14N4O4S MW: 298.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2'-(O-METHYL)-5-IODOURIDINE Order number: 211831 CAS: 34218-84-3 Purity: 95% Appearance: SOLID MF: C10H13IN2O6 MW: 384.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2'-(O-METHYL)-INOSINE Order number: 211832 CAS: 3881-21-8 Purity: 98% Appearance: WHITE POWDER MF: C11H14N4O5 MW: 282.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 3'-O-(T-BUTYLDIMETHYLSILYL)THYMIDINE Order number: 211833 CAS: 40733-27-5 Purity: 97% Appearance: SOLID MF: C16H28N2O5Si MW: 356.5 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |