We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 5'-O-TERT-BUTYLDIMETHYLSILYL-THYMIDINE Order number: 211834 CAS: 40733-28-6 Purity: 98% Appearance: SOLID MF: C16H28N2O5Si MW: 356.5 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: (Z)-1,5-Dimethylbicyclo[3.3.0]octane-3,7-dione Order number: 211835 CAS: 25137-84-2 Purity: 98% Appearance: n.a. MF: C25H22Cl2N2O7 MW: 533.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5'-AMINOIMIDAZOLE-4-CARBOXAMIDE-1-BETA-D-RIBOFURANOSYL 5'-MONOPHOSPHATE Order number: 211840 CAS: 3031-94-5 Purity: n.a.% Appearance: SOLID MF: C9H15N4O8P MW: 338.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 2'-O-(2-Methoxyethyl)uridine Order number: 211841 CAS: 223777-15-9 Purity: 95% Appearance: SOLID MF: C12H18N2O7 MW: 302.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Inosine, 1-methyl Order number: 211843 CAS: 2140-73-0 Purity: ?99% Appearance: SOLID MF: C11H14N4O5 MW: 282.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)adenosine Order number: 211844 CAS: 251647-48-0 Purity: 98% Appearance: SOLID MF: C41H41N5O8 MW: 731.8 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |