We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: METHYL 2-DEOXY-3,5-DI-O-P-TOLUOYL-D-*RIB OFURANOSIDE Order number: 211862 CAS: 4330-34-1 Purity: 96% Appearance: SOLID MF: C22H24O6 MW: 384.4 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 7H-Pyrrolo[2,3-d]pyriMidine, 4-chloro-5-iodo-7-(2,3,5-tri-O-benzoyl-?-D-ribofuranosyl)- Order number: 211863 CAS: 480439-89-2 Purity: 97% Appearance: n.a. MF: C32H23ClIN3O7 MW: 723.9 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 3'-O-(tert-butyldiMethylsilyl)-2'-deoxyadenosine Order number: 211864 CAS: 51549-31-6 Purity: 98% Appearance: n.a. MF: C16H27N5O3Si MW: 365.5 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Adenosine,N-benzoyl-2'-deoxy-3'-o-[(1,1-dimethylethyl)dimethylsilyl]- Order number: 211865 CAS: 51549-40-7 Purity: 97% Appearance: SOLID MF: C23H31N5O4Si MW: 469.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5'-(N-CYCLOPROPYL)CARBOXAMIDOADENOSINE Order number: 211867 CAS: 50908-62-8 Purity: n.a.% Appearance: n.a. MF: C13H16N6O4 MW: 320.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 7-METHYL-6-THIOGUANOSINE Order number: 211868 CAS: 55727-10-1 Purity: ?99% Appearance: n.a. MF: C11H15N5O4S MW: 313.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |