We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 5-HYDROXYMETHYL-2'-DEOXYURIDINE Order number: 211869 CAS: 5116-24-5 Purity: 95% Appearance: SOLID MF: C10H14N2O6 MW: 258.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: N4-BENZOYL-2'-O-METHYLCYTIDINE Order number: 211870 CAS: 52571-45-6 Purity: 98% Appearance: WHITE POWDER MF: C17H19N3O6 MW: 361.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Methyl 2,3,5-tri-O-benzyl-beta-D-ribofuranoside Order number: 211873 CAS: 55725-85-4 Purity: 98% Appearance: LIQUID MF: C27H30O5 MW: 434.5 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: N-(2-Hydroxyethyl)adenosine Order number: 211874 CAS: 4338-48-1 Purity: 98% Appearance: SOLID MF: C12H17N5O5 MW: 311.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2'-AZIDO-2'-DEOXYCYTIDINE Order number: 211875 CAS: 51034-68-5 Purity: n.a.% Appearance: SOLID MF: MW: MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2-Deoxy-alpha-D-erythropentofuranosyl chloride 3,5-bis(4-methylbenzoate) Order number: 211876 CAS: 4330-21-6 Purity: 90% Appearance: SOLID MF: C21H21ClO5 MW: 388.8 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |