We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: a-D-Glucopyranoside, methyl 6-amino-6-deoxy- Order number: 211878 CAS: 5155-47-5 Purity: ? 98 (HPLC)% Appearance: YELLOW POWDER MF: C7H15NO5 MW: 193.2 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: (2S)-2-[[9-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]amino]butanedioic acid Order number: 211880 CAS: 4542-23-8 Purity: 98% Appearance: SOLID MF: C14H17N5O8 MW: 383.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: ALPHA-THYMIDINE Order number: 211881 CAS: 4449-43-8 Purity: n.a.% Appearance: n.a. MF: MW: MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: N4-ANISOYL-2'-DEOXYCYTIDINE Order number: 211882 CAS: 48212-99-3 Purity: 97% Appearance: SOLID MF: C17H19N3O6 MW: 361.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2'-Bromo-2'-deoxy-D-uridine Order number: 211886 CAS: 4753-02-0 Purity: 95% Appearance: n.a. MF: C9H11BrN2O5 MW: 307.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2'-O-(2-Methoxyethyl)guanosine Order number: 211887 CAS: 473278-54-5 Purity: 98% Appearance: WHITE POWDER MF: C13H19N5O6 MW: 341.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |