We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: N6,3'-O-DIBENZOYL-2'-DEOXYADENOSINE Order number: 211889 CAS: 51549-54-3 Purity: n.a.% Appearance: n.a. MF: MW: MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2'-O-(tert-butyldiMethylsilyl)uridine Order number: 211891 CAS: 54925-71-2 Purity: 95% Appearance: n.a. MF: C15H26N2O6Si MW: 358.5 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2,6-Dichloro-9-[2,3-O-(1-Methylethylidene)-Beta-D-ribofuranosyl]-9H-purine Order number: 211892 CAS: 52678-40-7 Purity: 95% Appearance: SOLID MF: C13H14Cl2N4O4 MW: 361.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one Order number: 211893 CAS: 5627-05-4 Purity: 98% Appearance: SOLID MF: C9H14N2O6 MW: 246.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: CMC.HCI Order number: 211894 CAS: 51391-96-9 Purity: ?98?HPLC% Appearance: SOLID MF: C10H14ClN3O4 MW: 275.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate Order number: 211897 CAS: 52248-03-0 Purity: 98% Appearance: SOLID MF: C22H30N6O8S2 MW: 570.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |