Amino Acids, Nucleosides and Nucleotides

Amino Acids

We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.

Nucleosides and Nucleoside Phosphoramidites

We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.

Nucleotides

dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.

Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.

  • Amino Acids for Stapled Peptides
  • 2-Methylated Amino Acids
  • Peptide Labeling
  • Other Unnatural Amino Acids
  • Nucleosides
  • HNA Precursors
  • Morpholino Nucleosides
  • Nucleoside Phosphoramidites and Nucleotides
  • Nucleosides

    Structure Details
    Product Name: N6,3'-O-DIBENZOYL-2'-DEOXYADENOSINE
    Order number: 211889
    CAS: 51549-54-3
    Purity: n.a.%
    Appearance: n.a.
    MF:
    MW:
    MP: n.a. oC

    Description:
    This is a useful material for nucleoside and nucleotide chemistry.
    Product Name: 2'-O-(tert-butyldiMethylsilyl)uridine
    Order number: 211891
    CAS: 54925-71-2
    Purity: 95%
    Appearance: n.a.
    MF: C15H26N2O6Si
    MW: 358.5
    MP: n.a. oC

    Description:
    This is a useful material for nucleoside and nucleotide chemistry.
    Product Name: 2,6-Dichloro-9-[2,3-O-(1-Methylethylidene)-Beta-D-ribofuranosyl]-9H-purine
    Order number: 211892
    CAS: 52678-40-7
    Purity: 95%
    Appearance: SOLID
    MF: C13H14Cl2N4O4
    MW: 361.2
    MP: n.a. oC

    Description:
    This is a useful material for nucleoside and nucleotide chemistry.
    Product Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-hydroxy-1,3-diazinan-2-one
    Order number: 211893
    CAS: 5627-05-4
    Purity: 98%
    Appearance: SOLID
    MF: C9H14N2O6
    MW: 246.2
    MP: n.a. oC

    Description:
    This is a useful material for nucleoside and nucleotide chemistry.
    Product Name: CMC.HCI
    Order number: 211894
    CAS: 51391-96-9
    Purity: ?98?HPLC%
    Appearance: SOLID
    MF: C10H14ClN3O4
    MW: 275.7
    MP: n.a. oC

    Description:
    This is a useful material for nucleoside and nucleotide chemistry.
    Product Name: 5'-[[(3S)-3-AMino-3-carboxypropyl]Methylsulfonio]-5'-deoxy-Adenosine tosylate
    Order number: 211897
    CAS: 52248-03-0
    Purity: 98%
    Appearance: SOLID
    MF: C22H30N6O8S2
    MW: 570.6
    MP: n.a. oC

    Description:
    This is a useful material for nucleoside and nucleotide chemistry.