We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Cytidine-5'-triphosphate disodium salt Order number: 211555 CAS: 36051-68-0 Purity: 98% Appearance: SOLID MF: C9H14N3Na2O14P3 MW: 527.1 MP: n.a. oC Description: This is a useful building block for biosynthesis of nucleic acids. |
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Product Name: 5-Iodo-2'-deoxyuridine Order number: 211556 CAS: 54-42-2 Purity: 98% Appearance: SOLID MF: C9H11IN2O5 MW: 354.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 7-(2-Deoxy-?-L-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine Order number: 211557 CAS: 908130-61-0 Purity: 95% Appearance: WHITE POWDER MF: C11H13IN4O3 MW: 376.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Uridine 5'-(trihydrogen diphosphate), sodium salt Order number: 211558 CAS: 21931-53-3 Purity: 98% Appearance: SOLID MF: C9H11N2Na3O12P2 MW: 470.1 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: 2,3-O-Isopropylideneinosine Order number: 211559 CAS: 2140-11-6 Purity: 98% Appearance: POWDER MF: C13H18N4O5 MW: 310.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Adenosine-3',5'-cyclic monophosphate monosodium salt Order number: 211560 CAS: 37839-81-9 Purity: 98% Appearance: WHITE POWDER MF: C10H12N5NaO6P MW: 352.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |