We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(6-oxo-1H-purin-9(6H)-yl)tetrahydrofuran-3,4-diyl diacetate Order number: 211561 CAS: 3181-38-2 Purity: 97% Appearance: SOLID MF: C16H18N4O8 MW: 394.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Trifluorothymidine Order number: 211562 CAS: 70-00-8 Purity: ?98% Appearance: WHITE POWDER MF: C10H11F3N2O5 MW: 296.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 1-(Diaminomethylene)-3-(beta-D-ribofuranosyl)urea Picrate Order number: 211563 CAS: 4336-46-3 Purity: 80% Appearance: SOLID MF: C13H17N7O12 MW: 463.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: (2R,3R,4S,5R)-2-(Hydroxymethyl)-6-methoxytetrahydro-2H-pyran-3,4,5-triol Order number: 211565 CAS: 93302-26-2 Purity: 95% Appearance: SOLID MF: C7H14O6 MW: 194.2 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: (2R,3S)-5-Chloro-2-(((4-chlorobenzoyl)oxy)methyl)tetrahydrofuran-3-yl 4-chlorobenzoate Order number: 211566 CAS: 3601-90-9 Purity: 90% Appearance: SOLID MF: C19H15Cl3O5 MW: 429.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2?,3?-Dideoxy-5-iodouridine Order number: 211567 CAS: 105784-83-6 Purity: 97% Appearance: SOLID MF: C9H11IN2O4 MW: 338.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |