We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 5'-O-Dimethoxytrityl-N-isobutyryl-deoxyguanosine Order number: 211921 CAS: 68892-41-1 Purity: 95% Appearance: SOLID MF: C35H37N5O7 MW: 639.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 1-[(2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione Order number: 211922 CAS: 69256-17-3 Purity: 98% Appearance: SOLID MF: C10H13FN2O5 MW: 260.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-(Methoxycarbonyl)Methyl-2'-O-Methyl uridine Order number: 211923 CAS: 60197-31-1 Purity: 95% Appearance: n.a. MF: MW: MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5-Ethynyl uridine Order number: 211924 CAS: 69075-42-9 Purity: 95% Appearance: SOLID MF: C11H12N2O6 MW: 268.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: menisdaurin Order number: 211925 CAS: 67765-58-6 Purity: 98% Appearance: n.a. MF: MW: MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: METHYL-2,3,5-TRI-O-BENZOYL-A-D-*ARABINOFURANOSIDE Order number: 211926 CAS: 7473-42-9 Purity: 98% Appearance: SOLID MF: C27H24O8 MW: 476.5 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |