We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 5'-O-(TERT-BUTYLDIMETHYLSILYL)-5-IODO-2'-DEOXYCYTIDINE Order number: 211937 CAS: 666848-11-9 Purity: 97% Appearance: SOLID MF: C15H26IN3O4Si MW: 467.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 6-THIO-2'-DEOXYGUANOSINE Order number: 211941 CAS: 789-61-7 Purity: 98% Appearance: SOLID MF: C10H13N5O3S MW: 283.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 1-[4-Amino-7-(3-hydroxypropyl)-5-(4-methylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-6-yl]-2-fluoroethanone Order number: 211944 CAS: 821794-92-7 Purity: 99% Appearance: SOLID MF: C18H19FN4O2 MW: 342.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: URIDYLIC ACID Order number: 211946 CAS: 84-53-7 Purity: 98% Appearance: SOLID MF: MW: MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: N2-Isobutyryl-2'-Fluoro-2'-deoxyguanosine Order number: 211947 CAS: 80681-25-0 Purity: 98% Appearance: SOLID MF: C14H18FN5O5 MW: 355.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: N6-Benzoyl-2'-O-Methyl-adenosine Order number: 211948 CAS: 85079-00-1 Purity: 98% Appearance: WHITE POWDER MF: C18H19N5O5 MW: 385.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |