We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Adenosine 5'-(trihydrogen diphosphate), P'-?-D-glucopyranosyl ester, disodium salt (9CI) Order number: 211344 CAS: 102129-65-7 Purity: ?93% Appearance: SOLID MF: C10H12N5O6P2- MW: 360.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Cytidine, 5-bromo-2'-deoxy- Order number: 211345 CAS: 1022-79-3 Purity: 97% Appearance: SOLID MF: C9H12BrN3O4 MW: 306.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: ?-D-Glucopyranosiduronic acid, 5-bromo-4-chloro-1H-indol-3-yl, compd. with cyclohexanamine (1:1) Order number: 211346 CAS: 114162-64-0 Purity: 99% Appearance: SOLID MF: C20H26BrClN2O7 MW: 521.8 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Uridine, 2'-deoxy-2',2'-difluoro- Order number: 211347 CAS: 114248-23-6 Purity: 95% Appearance: SOLID MF: C9H10F2N2O5 MW: 264.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Uridine, 5-iodo- Order number: 211348 CAS: 1024-99-3 Purity: 98% Appearance: SOLID MF: C9H11IN2O6 MW: 370.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Cytidine, N-acetyl-2'-O-methyl- Order number: 211350 CAS: 113886-71-8 Purity: 97% Appearance: SOLID MF: C12H17N3O6 MW: 299.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |