We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Cytidine,N-acetyl-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]- Order number: 211951 CAS: 85335-73-5 Purity: 95% Appearance: OFF-WHITE POWDER MF: C23H41N3O7Si2 MW: 527.8 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 1-((6aR,8R,9aR)-2,2,4,4-tetraisopropyl-9-oxotetrahydro-6H-furo[3,2-f ][1,3,5,2,4]trioxadisilocin-8-yl)pyriMidine-2,4(1H,3H)-dione Order number: 211952 CAS: 84828-97-7 Purity: 95% Appearance: n.a. MF: C21H36N2O7Si2 MW: 484.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 5'-O-(4,4'-DiMethoxytrityl)-3'-O-t-butyldiMethylsilyl uridine Order number: 211953 CAS: 81246-81-3 Purity: 95% Appearance: SOLID MF: C36H44N2O8Si MW: 660.8 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Baicalin methyl ester Order number: 211954 CAS: 82475-03-4 Purity: 98% Appearance: n.a. MF: C22H20O11 MW: 460.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: N-Benzoyl-3',5'-O-[1,1,3,3-tetrakis(1-methylethyl)-1,3-disiloxanediyl]adenosine Order number: 211955 CAS: 79154-57-7 Purity: 97% Appearance: n.a. MF: C29H43N5O6Si2 MW: 613.9 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: (2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate Order number: 211958 CAS: 874638-94-5 Purity: 98% Appearance: n.a. MF: C31H26FN3O7 MW: 571.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |