We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: BenzaMide, N-[1-(3,5-di-O-benzoyl-2-C-Methyl-?-D-arabinofuranosyl)-1,2-dihydro-2-oxo-4-pyriMidinyl]- Order number: 211959 CAS: 863329-62-8 Purity: 96% Appearance: n.a. MF: C31H27N3O8 MW: 569.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Cytidine, N-benzoyl-2^-deoxy-2^-Methylene-,3^,5^-dibenzoate(9CI) Order number: 211960 CAS: 863329-63-9 Purity: 98% Appearance: SOLID MF: C31H25N3O7 MW: 551.5 MP: n.a. oC Description: Useful building block for nucleoside and nucleotide chemistry |
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Product Name: (2'R)- 2'-Deoxy-2'-fluoro-2'-methylcytidine 3',5'-bis(2-methylpropanoate) Order number: 211961 CAS: 940908-79-2 Purity: 99% Appearance: n.a. MF: C18H26FN3O6 MW: 399.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2-AMINO-4-METHOXY-7-(BETA-D-2-DEOXYRIBOFURANOSYL)PYRROLO[2,3-D]PYRIMIDINE Order number: 211964 CAS: 86392-74-7 Purity: n.a.% Appearance: n.a. MF: C12H16N4O4 MW: 280.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2',3'-DIDEOXY-3'-FLUORO-GUANOSINE Order number: 211967 CAS: 92562-88-4 Purity: n.a.% Appearance: n.a. MF: C10H12FN5O3 MW: 269.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 4-Methylumbelliferyl-beta-D-glucuronid Hydrat 4-Methylumbelliferyl-beta-D-glucuronide Hydrate Order number: 211968 CAS: 881005-91-0 Purity: 98% Appearance: n.a. MF: C16H18O10 MW: 370.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |