We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: S-(5'-Adenosyl)-L-Methionine chloride dihydrochloride Order number: 211970 CAS: 86867-01-8 Purity: 75% Appearance: SOLID MF: C15H25Cl3N6O5S MW: 507.8 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 6-AZACYTOSINE Order number: 211971 CAS: 931-85-1 Purity: n.a.% Appearance: n.a. MF: C3H4N4O MW: 112.1 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: Psoralenoside Order number: 211974 CAS: 905954-17-8 Purity: 98% Appearance: n.a. MF: MW: MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Isopsoralenoside Order number: 211975 CAS: 905954-18-9 Purity: 98% Appearance: n.a. MF: MW: MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 4'-ethynyl-2-fluoro-2'-deoxyadenosine Order number: 211976 CAS: 865363-93-5 Purity: 98% Appearance: SOLID MF: C12H12FN5O3 MW: 293.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 8-CPT-cAMP Order number: 211978 CAS: 93882-12-3 Purity: 98% Appearance: SOLID MF: C16H14ClN5NaO6PS MW: 493.8 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |