We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 2-Chloro-N-[(3-iodophenyl)methyl]-2',3'-O-(1-methylethylidene) Adenosine Order number: 211979 CAS: 1000980-71-1 Purity: 95% Appearance: SOLID MF: C20H21ClIN5O4 MW: 557.8 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: (2R,3S,5R)-2-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-5-(6-(methylamino)-9H-purin-9-yl)tetrahydrofuran-3-ol Order number: 211980 CAS: 98056-69-0 Purity: n.a.% Appearance: WHITE POWDER MF: C32H33N5O5 MW: 567.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: (-)-Cyclocytidine hydrochloride Order number: 211982 CAS: 10212-25-6 Purity: 97% Appearance: SOLID MF: C9H12ClN3O4 MW: 261.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Guanosine, 8-bromo-2'-deoxy- Order number: 211988 CAS: 13389-03-2 Purity: 98% Appearance: SOLID MF: C10H12BrN5O4 MW: 346.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: a-D-erythro-Pentofuranose, 2-deoxy-2,2-difluoro-, 3,5-dibenzoate Order number: 211990 CAS: 143157-22-6 Purity: 95% Appearance: SOLID MF: MW: MP: n.a. oC Description: Useful building block for nucleoside and nucleotide chemistry |
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Product Name: b-L-Ribofuranose, tetraacetate Order number: 211993 CAS: 144490-03-9 Purity: 97% Appearance: SOLID MF: C13H18O9 MW: 318.3 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |