We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: (2S,3S,4S,5R,6R)-6-(5,6-dihydroxy-4-oxo-2-phenylchromen-7-yl)oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Order number: 211997 CAS: 21967-41-9 Purity: 90% Appearance: SOLID MF: C21H18O11 MW: 446.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: a-D-Ribofuranose, 1,3,5-tribenzoate Order number: 211998 CAS: 22224-41-5 Purity: 97% Appearance: WHITE POWDER MF: C26H22O8 MW: 462.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one,2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-7-methyl-,(2R,3R,3aS,9aR)- Order number: 211999 CAS: 22423-26-3 Purity: 98% Appearance: WHITE POWDER MF: C10H12N2O5 MW: 240 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Cytidine, 2'-O-methyl- Order number: 212000 CAS: 2140-72-9 Purity: 98% Appearance: WHITE SOLID POWDER MF: C10H15N3O5 MW: 257 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: D-Allononitrile, 2,5-anhydro-, 3,4,6-tribenzoate Order number: 212001 CAS: 23316-67-8 Purity: 95% Appearance: SOLID MF: C27H21NO7 MW: 471.5 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Uridine, 2'-amino-2'-deoxy- Order number: 212003 CAS: 26889-39-4 Purity: 98% Appearance: SOLID MF: C9H13N3O5 MW: 243.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |