We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 5-iodo-7-b-D-ribofuranosyl- Order number: 212004 CAS: 24386-93-4 Purity: ?98% Appearance: SOLID MF: C11H13IN4O4 MW: 392.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Thymidine, 3'-deoxy-3'-fluoro- Order number: 212005 CAS: 25526-93-6 Purity: 98% Appearance: SOLID MF: C10H13FN2O4 MW: 244.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Benzeneacetonitrile,a-[(6-O-b-D-glucopyranosyl-b-D-glucopyranosyl)oxy]-, (aR)- Order number: 212006 CAS: 29883-15-6 Purity: 95% Appearance: SOLID MF: C20H27NO11 MW: 457.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 9H-Purin-6-amine, 9-(5-O-phosphono-b-D-arabinofuranosyl)- Order number: 212007 CAS: 29984-33-6 Purity: 98% Appearance: n.a. MF: C10H14N5O7P MW: 347.2 MP: n.a. oC Description: This is a useful material for nucleotide chemistry and biology. |
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Product Name: Adenosine,N-benzoyl-2'-deoxy-, monohydrate (9CI) Order number: 212008 CAS: 305808-19-9 Purity: 98% Appearance: SOLID MF: MW: MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Thymidine, 3'-deoxy- Order number: 212009 CAS: 3416-05-5 Purity: 97% Appearance: WHITESOLID POWDER MF: C10H14N2O4 MW: 226.2 MP: n.a. oC Description: Useful building block for nucleoside and nucleotide chemistry |