We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: L-Thymidine Order number: 212010 CAS: 3424-98-4 Purity: 98% Appearance: SOLID MF: C10H14N2O5 MW: 242.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Adenosine, 2-chloro-N-cyclopentyl- Order number: 212013 CAS: 37739-05-2 Purity: 98% Appearance: n.a. MF: C15H20ClN5O4 MW: 369.8 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: b-D-Glucopyranosiduronic acid, 1H-indol-3-yl Order number: 212014 CAS: 35804-66-1 Purity: ? 99 (TLC)% Appearance: n.a. MF: C20H28N2O7 MW: 408.4 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Tobramycin Order number: 212016 CAS: 32986-56-4 Purity: n.a.% Appearance: SOLID MF: C18H37N5O9 MW: 467.5 MP: n.a. oC Description: This is a useful starting material. |
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Product Name: 9H-Purine, 6-chloro-9-(2-deoxy-b-D-erythro-pentofuranosyl)- Order number: 212017 CAS: 4594-45-0 Purity: 98% Appearance: WHITE POWDER MF: C10H11ClN4O3 MW: 270.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]- Order number: 212019 CAS: 40615-39-2 Purity: 98% Appearance: QUASI WHITE FLOCCULENT POWDER MF: C31H32N2O7 MW: 544.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |