We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: Adenosine, 2',3'-dideoxy- Order number: 212021 CAS: 4097-22-7 Purity: 98% Appearance: SOLID MF: C10H13N5O2 MW: 235.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: b-D-Ribofuranoside, methyl 2,3-O-(1-methylethylidene)- Order number: 212022 CAS: 4099-85-8 Purity: 95% Appearance: LIQUID MF: C9H16O5 MW: 204.2 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 9H-Purine, 6-chloro-9-[2,3-O-(1-methylethylidene)-b-D-ribofuranosyl]- Order number: 212023 CAS: 39824-26-5 Purity: 97% Appearance: SOLID MF: C13H15ClN4O4 MW: 326.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Cytidine, 2'-deoxy-, monohydrochloride Order number: 212024 CAS: 3992-42-5 Purity: 98% Appearance: SOLID MF: C9H14ClN3O4 MW: 263.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Guanosine, 8-bromo- Order number: 212025 CAS: 4016-63-1 Purity: 97% Appearance: SOLID MF: C10H12BrN5O5 MW: 362.1 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: b-D-Ribofuranoside, methyl 2,3-O-(1-methylethylidene)-,4-methylbenzenesulfonate Order number: 212026 CAS: 4137-56-8 Purity: 98% Appearance: SOLID MF: C16H22O7S MW: 358.4 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |