We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: a-D-Ribofuranoside, methyl3,5-bis-O-[(2,4-dichlorophenyl)methyl]-2-C-methyl- Order number: 212027 CAS: 443642-31-7 Purity: n.a.% Appearance: n.a. MF: C21H22Cl4O5 MW: 496.2 MP: n.a. oC Description: Useful building block for nucleoside and nucleotide chemistry |
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Product Name: Thymidine, 3'-amino-3'-deoxy- Order number: 212028 CAS: 52450-18-7 Purity: 98% Appearance: WHITE POWDER MF: C10H15N3O4 MW: 241.2 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: D-Arabinofuranose, 2,3,5-tris-O-(phenylmethyl)-, 4-nitrobenzoate Order number: 212029 CAS: 52522-49-3 Purity: 97% Appearance: SOLID MF: C33H31NO8 MW: 569.6 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: 2-Deoxy-d-ribose Order number: 212032 CAS: 533-67-5 Purity: 98% Appearance: SOLID MF: C5H10O4 MW: 134.1 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: D-(-)-Ribose Order number: 212033 CAS: 50-69-1 Purity: 97% Appearance: WHITE POWDER MF: C5H10O5 MW: 150.1 MP: n.a. oC Description: This is a useful starting material for nucleoside chemistry. |
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Product Name: Adenosine, N-benzoyl-2'-deoxy-5'-O-[(1,1-dimethylethyl)dimethylsilyl]- Order number: 212034 CAS: 51549-39-4 Purity: 97% Appearance: n.a. MF: MW: MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |