We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: [(2R,3S,4R,5R)-5-(4-benzamido-2-oxo-1,2-dihydropyrimidin-1-yl)-3-(benzoyloxy)-4-fluoro-4-methyloxolan-2-yl]methyl benzoate Order number: 212070 CAS: 2173637-26-6 Purity: 97% Appearance: n.a. MF: C31H26FN3O7 MW: 571.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: SAMe-1?4-Butanedisulfonate Order number: 212076 CAS: 101020-79-5 Purity: 95% Appearance: SOLID MF: C42H74N12O28S8 MW: 1452 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Inosine, compd. with 1-(dimethylamino)-2-propanol4-(acetylamino)benzoate (salt) (1:3)OTHER CA INDEX NAMES:2-Propanol, 1-(dimethylamino)-, 4-(acetylamino)benzoate (salt),compd. with inosine (3:1)Benzoi Order number: 212079 CAS: 36703-88-5 Purity: 98% Appearance: SOLID MF: C52H78N10O17 MW: 1115 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Ribostamycin Sulfate Order number: 212081 CAS: 53797-35-6 Purity: 98% Appearance: SOLID MF: C17H34N4O10 MW: 454.5 MP: n.a. oC Description: This is a useful starting material. |
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Product Name: Deoxyribonucleic acid sodium salt (from calf thymus) Order number: 212083 CAS: 73049-39-5 Purity: 85% Appearance: SOLID MF: MW: MP: n.a. oC Description: Useful building block for nucleoside and nucleotide chemistry |
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Product Name: O6-Methyl-deoxyguanosine Order number: 212085 CAS: 964-21-6 Purity: n.a.% Appearance: SOLID MF: C11H15N5O4 MW: 281.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |