We offer Fmoc-protected unnatural amino acids for the synthesis of peptides for biological research and pharmaceutical development. By introducing conformational constraints, the peptides may have one or several of the following features: 1. enhancement of peptide backbone helicity for better target binding; 2. tunable hydrophobicity for desired cellular permeability and cytotoxicity; and 3. enhancement of peptide stability against proteolytic breakdown.
We offer nucleosides with modifications in both the nucleic acid base and the sugar component of the molecules. Nucleoside phosphoramidites are extremely useful chemical building blocks for the chemical synthesis of RNA-targeting drugs such as antisense oligonucleotides, aptamers, and siRNAs which have exhibited promises for treating diseases including muscular dystrophy, neuropathies, and macular degeneration.
dNTP, NTP, and modified nucleotides have exhibited a wide range of applications in PCR, RT-PCR, cRNA synthesis, RCA, MDA, DNA labeling, and sequencing. dNTPs are chemical building blocks in the commercial manufacture of mRNA vaccines using in vitro transcription method.
Inquire about our bulk quantities for the manufacture of oligonucleotide drug ingredients and large-scale production of mRNAs.
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Product Name: ((3aR,4R,6R,6aR)-6-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol Order number: 212086 CAS: 158078-04-7 Purity: 97% Appearance: SOLID MF: C14H16ClN3O4 MW: 325.7 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: (2R,3R,4R,5R)-5-((Benzoyloxy)Methyl)-2-(2,4-Dioxo-3,4-Dihydropyrimidin-1(2H)-Yl)-3-Ethynyltetrahydrofuran-3,4-Diyl Dibenzoate Order number: 212089 CAS: 1443997-55-4 Purity: 95% Appearance: n.a. MF: C32H24N2O9 MW: 580.5 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: Uridine, 5-chloro-2'-deoxy- Order number: 212091 CAS: 50-90-8 Purity: 98% Appearance: SOLID MF: C9H11ClN2O5 MW: 262.6 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 3H-Imidazo[2,1-i]purine, 3-(2-deoxy-b-D-erythro-pentofuranosyl)- Order number: 212092 CAS: 68498-25-9 Purity: n.a.% Appearance: SOLID MF: C12H13N5O3 MW: 275.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: b-D-Ribofuranuronamide, 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl- Order number: 212093 CAS: 35920-39-9 Purity: n.a.% Appearance: WHITE POWDER MF: C12H16N6O4 MW: 308.3 MP: n.a. oC Description: This is a useful material for nucleoside and nucleotide chemistry. |
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Product Name: 2,3,4-Tri-O-acetyl-1-O-[4-(Hydroxymethyl)-2-nitrophenyl]-beta-D-glucuronideMethylEster Order number: 212098 CAS: 148579-94-6 Purity: 97% Appearance: SOLID MF: C20H23NO13 MW: 485.4 MP: n.a. oC Description: This is a useful starting material. |